Colorectal Cancer Now Leads Cancer Death in Americans Under 50

Wednesday, March 4, 2026

The Oregon Clinic

Banner for Colon Cancer Awareness Month

Recent news about the passing of actor James Van Der Beek at age 48 from colorectal cancer came shortly after the Journal of the American Medical Association (JAMA) released an alarming new statistic: colorectal cancer is now the leading cause of cancer deaths in people under age 50.

Unfortunately, despite the increase in colorectal cancer diagnoses and deaths, many adults between ages 45 and 50 are still not getting screened.

Know the Warning Signs

One reason colorectal cancer is so deadly in younger adults is that it is often caught late. Many people under 50 think colorectal cancer wouldn’t affect them, leading them to overlook early symptoms like abdominal pain, blood in the stool, constipation, diarrhea, decreased appetite, and unexplained weight loss.

Knowing these warning signs, getting your first screening at 45 or earlier, and talking to your doctor about any changes are important steps to prevent a late-stage diagnosis.

Colonoscopy is The Gold Standard for Colon Cancer Screening

The American Cancer Society, U.S. Preventive Services Task Force, and American College of Gastroenterology all recommend starting regular colorectal cancer screening at age 45. If you have a family history of colorectal cancer or other high-risk factors, you may need to start even earlier.

Colonoscopy is the gold standard screening because it’s the only test that can both detect early cancer and prevent cancer from developing. During the procedure, a doctor will look at the entire colon, find precancerous polyps, and remove them right away. This stops cancer before it has a chance to grow.

Why not Cologuard?

A Team Approach to Colon Cancer Care

Take the Next Step, Get the Best Test

Click here to get started with colonoscopy screening.

Learn more about The Oregon Clinic Gastroenterology